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KMID : 0931320130130040220
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대한상부위장관.헬리코박터학회지
2013 Volume.13 No. 4 p.220 ~ p.223
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Immune Response to Helicobacter pylori Infection
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Han Jae-Pil
Hong Su-Jin
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Abstract
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Helicobacter pylori infection leads to immune responses associated with almost all mechanism of innate and acquired immunity. However, clinical manifestation of H. pylori infection varies from asymptomatic gastritis to gastric cancer. The balance between harmful injury in gastric mucosa and protective role of immune mechanisms may be influenced by the variability of bacterial viru-lence factors, host susceptibility, and environmental factors. In this review, we describe the inflammatory response of H. pylori in-fection and protective mechanism against H. pylori infection. Better understanding of the mechanism of the immune response to H. pylori infection can be helpful in the development of new therapeutic strategies and prophylactic vaccine
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KEYWORD
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Helicobacter pylori, Immunity
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